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    The invention provides a preparation method of cetirizine hydrochloride with high purity. The method comprises: 4-[(4-chlorophenyl) phenyl]-1-hydroxyethyl piperazine and sodium chloroacetate are used as reaction substrates and alkali metal hydroxide is used as catalyst for the condensation reaction in organic solvent at 5-40 DEG C; when the condensation reaction is finished, cetirizine mother

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    The concentration of data near the fitted line for ozone and carbonate radical data in Figure 5 undoubtedly indicates that these data are of high quality, but probably also reflects the relatively simple substitutions of the anilines included in these data sets (mostly single methyl, methoxy, or halogen substituents) and homogeneity of the

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    Discovery of Asciminib (ABL001), an Allosteric Inhibitor

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    A Zn-Dependent Metallopeptidase Is Responsible

    N-Methyl-N′-nitro-N-nitrosoguanidine (MNNG) mutagenesis of LsbB-sensitive strain BGMN1-596.. L. lactis BGMN1-596 was grown overnight at 30°C in 10 ml of GM17 broth. The overnight culture was diluted 100-fold in 50 ml of GM17 broth and incubated at 30°C until the end of the exponential growth phase.