use of alternate thiol accelerators for crosslinking
US6956071B2 - Use of alternate thiol accelerators
Nitrogen-containing thiols containing at least one functional group —N═(SH)— have been found to be useful alternate accelerators along with activators such as zinc oxides. Particular nitrogen-containing thiols include, but are not necessarily limited to, 2-mercaptobenzoxazole (MBO), 2-mercapto-5-methyl-1,3,4-thiadiazole (MMTD), and
USE OF ALTERNATE THIOL ACCELERATORS FOR CROSSLINKING RUBBER
The Rubber Response for the control blend (Ex. 1B) was 3.26°C per percent Finaprene 502. This is within the normal range for Asphalt A. The Rubber Response for each of the two alternative thiol accelerators was increased, relative to the Control blend. The increase was approximately 0.25°C per percent rubber for each of the alternative
Thiol Reactive Crosslinkers for Bioconjugation
Thiol reactive crosslinkers are one of the most common classes of crosslinkers in bioconjugation ().The popularity of conjugation to a thiol is due in part to its presence in many proteins, but they are not as prevalent as amines, which are another site for conjugation.
A Benzoxazole Sulfenamide Accelerator: Synthesis, Structure
Use of Alternate Thiol Accelerators for Crosslinking Rubber in Asphalt. J. R. Butler; It is suggested that the induction period prior to crosslinking is occasioned by the inactivity of Zn(mbt
Photoinitiated cross-linking of a thiol–methacrylate system
The photoinitiated thiol–ene cross-linking of a dimethacrylate polyether of Bisphenol A and pentaerythritol tetrakis 2-mercaptopropionate was studied in the presence of 2,2-dimethyl-2-hydroxy acetophenone (Darocur 1173). Two complementary techniques were used: photocalorimetry and real-time infrared spectroscopy.
Chemical cross-linking with thiol-cleavable reagents combined
The strategy of chemical cross-linking combined with differential MALDI-MS peptide mapping (+ thiol reagent) enabled localization of the interface region(s) of the complexes studied and clearly demonstrates the utility of such an approach to obtain structural information on interacting noncovalent complexes.
Maleimide CrossLinked Bioactive PEG Hydrogel Exhibits
use, ease in incorporating various functionalities, and commer-cial availability of reagents. In the present study, we explored the use of an alternative reactive cross-linking moiety for PEG hydrogels, the maleimide functional group. We demonstrate several advantages over other cross-linking chemistries, namely
Polyethylene Glycol (PEG) and Pegylation of Proteins | Thermo
Thermo Scientific Pierce BM (PEG) 3 is a bismaleimide-activated PEG compound for crosslinking between sulfhydryl (—SH) groups in proteins and other thiol molecules. The maleimide groups at either end of the PEG3 spacer react specifically and efficiently with reduced sulfhydryls at pH 6.5-7.5 to form stable thioether bonds.
Amine-Reactive Crosslinker Chemistry | Thermo Fisher
The simplest, most common and versatile techniques for crosslinking or labeling peptides and proteins such as antibodies involve the use of chemical groups that react with primary amines (–NH2). Primary amines exist at the N-terminus of each polypeptide chain and in the side-chain of lysine (Lys, K) amino acid residues.
Siloxane crosslinks with dynamic bond exchange enable shape
To verify the effect of our composition on the network strand length, we first characterized the molecular weight of thiol-terminated oligomer chains before adding the crosslinker (after the first
Thiol-Methylsulfone-Based Hydrogels for 3D Cell Encapsulation
Thiol-maleimide and thiol-vinylsulfone cross-linked hydrogels are widely used systems in 3D culture models, in spite of presenting uncomfortable reaction kinetics for cell encapsulation: too fast (seconds for thiol-maleimide) or too slow (minutes-hours for thiol-vinylsulfone). Here, we introduce the thiol-methylsulfone reaction as alternative cross-linking chemistry for cell encapsulation
Regulation of mechanical properties of diene rubber cured
Generally, sulfur-based crosslinking requires a number of toxic additives, including activators and accelerators. In addition, the amount of these additive can be as high as 8–10 parts related to 100 parts of gum and the toxic additives are usually no less than 1 part per 100 parts of gum [ 36 ].