dimethylthiarum disulfide: new sulfur transfer reagent

  • dimethylthiarum disulfide | springerlink

    Dimethylthiarum Disulfide | SpringerLink

    Dimethylthiarum disulfide (DTD) has been developed as a new and efficient sulfur-transfer reagent for automated synthesis of phosphorothioate oligonucleotides using phosphoramidite chemistry. The traditional four-step automated oligonucleotide synthesis has been compressed to three-step protocol using DTD.

  • dimethylthiarum disulfide: new sulfur transfer reagent

    Dimethylthiarum disulfide: new sulfur transfer reagent

    Dimethylthiarum disulfide (DTD) has been developed as a new and efficient sulfur-transfer reagent for automated synthesis of phosphorothioate oligonucleotides using phosphoramidite chemistry. The traditional four-step automated oligonucleotide synthesis has been compressed to three-step protocol using DTD.

  • dimethylthiarum disulfide: new sulfur transfer reagent

    Dimethylthiarum Disulfide: New Sulfur Transfer Reagent

    Dimethylthiarum disulfide (DTD) has been developed as a new and efficient sulfur-transfer reagent for automated synthesis of phosphorothioate oligonucleotides using phosphoramidite chemistry.

  • dimethylthiarum disulfide: new sulfur transfer reagent

    Dimethylthiarum disulfide: new sulfur transfer reagent

    Request PDF | Dimethylthiarum disulfide: new sulfur transfer reagent in phosphor-othioates oligonucleotide synthesis | Dimethylthiarum disulfide (DTD) has been developed as a new and efficient

  • synthesis of oligodeoxyribonucleoside phosphorothioates using

    Synthesis of oligodeoxyribonucleoside phosphorothioates using

    Dimethylthiarum disulfide (DTD) has been developed as a new and efficient sulfur-transfer reagent for automated synthesis of phosphorothioate oligonucleotides using phosphoramidite chemistry. The

  • cas 2438-90-6 | n,n'-dimethylthioperoxydicarbamic acid | cas

    CAS 2438-90-6 | N,N'-dimethylthioperoxydicarbamic acid | CAS

    Dimethylthiarum disulfide: new sulfur transfer reagent in phosphorothioates oligonucleotide synthesis. Methods in molecular biology (Clifton, N.J.) 20050101: A short, novel, and cheaper procedure for oligonucleotide synthesis using automated solid phase synthesizer. Nucleosides, nucleotides & nucleic acids 20030101

  • zhiwei wang's research works | ionis pharmaceuticals

    Zhiwei Wang's research works | Ionis Pharmaceuticals

    Dimethylthiarum disulfide (DTD) has been developed as a new and efficient sulfur-transfer reagent for automated synthesis of phosphorothioate oligonucleotides using phosphoramidite chemistry.

  • disulfide

    Disulfide

    Thiol–disulfide exchange is a chemical reaction in which a thiolate group −S − attacks a sulfur atom of a disulfide bond −S−S−. The original disulfide bond is broken, and its other sulfur atom is released as a new thiolate, carrying away the negative charge.

  • organic sulfur chemistry. 26. synthesis and reactions of some

    Organic sulfur chemistry. 26. Synthesis and reactions of some

    Investigation of Sulfur Extrusion from a Cyclic Dialkoxy Disulfide. The Journal of Organic Chemistry 2007, 72 (10) , 3906-3908. DOI: 10.1021/jo062190n. Eli Zysman-Colman,, Charles B. Abrams, and, David N. Harpp. Synthesis of New Cyclic Thionosulfites.

  • a simple synthesis of sugar disulfides using

    A simple synthesis of sugar disulfides using

    ELSEVIER CARBOHYDRATE RESEARCH Carbohydrate Research 301 (1997) 221-224 Note A simple synthesis of sugar disulfides using tetrathiomolybdate as a sulfur-transfer reagent Debjani Bhar, Srinivasan Chandrasekaran Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India Received 24 September 1996; accepted 6 March 1997 Keywords: Sugar disulfide; Tetrathiomolybdate

  • large-scale synthesis of oligonucleotide phosphorothioates

    Large-Scale Synthesis of Oligonucleotide Phosphorothioates

    A commercially available and inexpensive compound, 3-amino-1,2,4-dithiazole-5-thione (ADTT), is discovered to be a new sulfur-transfer reagent for solid-phase synthesis of oligonucleotide phosphorothioates via the phosphoramidite method. The efficiency of ADTT was investigated by solid-phase syntheses of dinucleotide and oligonucleotide phosphorothioates. The results show that ADTT is a highly

  • sulfur allotrope chemistry—s10 an effective two-sulfur

    Sulfur allotrope chemistry—S10 an effective two-sulfur

    Pergamon Tetrahedron Letters 40 (1999) 7961-7964 TETRAHEDRON LETTERS Sulfur allotrope chemistry--S lO an effective two-sulfur transfer reagent Pierre Lestd-Lasserre and David N. Harpp * Department of Chemistry, McGill University, 801 Sherbrooke St. W., Montreal, Quebec, Canada H3A 2K6 Received 6 August 1999; accepted 24 August 1999 Abstract The chemistry of one of the sulfur allotropes has

  • three sulfur atom insertion into the s s bond—pentasulfide

    Three sulfur atom insertion into the S S bond—pentasulfide

    Three equivalents of reagent 1 were required to completely react with diisopropyl disulfide (2j). The pentasulfide 3j that formed underwent rapid disproportionation on a silica gel column. The reaction of 1 with t-butyl disulfide (2k) provided t-butyl pentasulfide (3k) only as a minor product even when excess 1 is used in the reaction mixture.